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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T8682 | Vazegepant hydrochloride | Vazegepant HCl | CGRP Receptor |
Vazegepant hydrochloride (Vazegepant HCl) is the first intranasal gepant for the acute treatment of migraine and has announced a positive phase II/III study. | |||
T17194 | Ubrogepant | MK-1602 | CGRP Receptor |
Ubrogepant (MK-1602) is an antagonist of calcitonin gene-related peptide receptor that can be used in the acute treatment of migraine studies. | |||
T12293L | Olcegepant | BIBN-4096,BIBN 4096BS | CGRP Receptor |
Olcegepant (BIBN-4096) is an effective and selective non-peptide calcitonin gene-related peptide 1 (CGRP1) receptor antagonist (IC50 of 0.03 nM and Ki of 14.4 pM for human CGRP). | |||
TP1040 | Calcitonin (salmon) | Calcitonin salmon,Salmon calcitonin | CGRP Receptor |
Calcitonin (salmon), a calcium regulating hormone, is used to treat osteoporosis in women who are at least 5 years past menopause. | |||
T4610 | Rimegepant | BMS 927711,BMS-927711,BMS927711,BHV-3000 | CGRP Receptor |
Rimegepant (BMS 927711) is a highly potent, oral calcitonin gene-related peptide (CGRP) receptor antagonist with a Ki value of 0.027 nM. | |||
T6590 | MK-3207 Hydrochloride | MK-3207 HCl | CGRP Receptor |
MK-3207 Hydrochloride (MK-3207 HCl) is a potent CGRP receptor antagonist with IC50 and Kiof 0.12 nM and 0.022 nM, highly selective versus human AM1, AM2, CTR, and AMY3. Phase 2. | |||
T13453 | CGRP antagonist 1 | CGRP Receptor | |
CGRP antagonist 1 is a potent CGRP receptor antagonist with Ki values of 35 nM and IC50 values of 57 nM, respectively.CGRP antagonist 1 can be used for the study of cardiovascular and neurovascular diseases. | |||
TP1323 | CGRP 8-37 (rat) | CGRP Receptor | |
CGRP 8-37 (rat) is a CGRP receptor antagonist, a CGRP fragment with potential anti-injury effects that induces arterial relaxation. | |||
T21581L | AC 187 Acetate | AC 187 Acetate (151804-77-2 Free base) | Amylin Receptor |
AC 187 Acetate is a potent antagonist of amylin receptor .AC 187 shows more selective for amylin receptor than calcitonin and CGRP receptors. | |||
TP1200 | CGRP (83-119), rat TFA | Calcitonin Gene Related Peptide(83-119), rat TFA | Others |
CGRP (83-119), rat TFA (Calcitonin Gene Related Peptide(83-119), rat TFA) is a 37 amino acid calcitonin family of neuropeptide, acts through calcitonin receptor-like receptor. | |||
TP2167 | β-CGRP, human acetate | β-CGRP, human acetate (101462-82-2 free),CGRP-II (Human) (acetate),Human β-CGRP acetate | CGRP Receptor |
β-CGRP, human acetate is one of calcitonin peptides and acts via the complex of receptor-activity-modifying protein (RAMP) and calcitonin-receptor-like receptor (CRLR) (IC50s: 1 nM and 300 nM for CRLR/RAMP1 and CRLR/RAMP... | |||
TP1134L | HCGRP-(8-37) acetate | HCGRP-(8-37) acetate (119911-68-1 free base) | CGRP Receptor |
HCGRP-(8-37) acetate is a human calcitonin gene-related peptide (hCGRP) fragment acetate and also an antagonist of CGRP receptor. | |||
TP1257L | Adrenomedullin (AM) (22-52), human acetate | Adrenomedullin (AM) (22-52), human acetate(159899-65-7 Free base) | CGRP Receptor |
Adrenomedullin (AM) (22-52), human acetate is an antagonist of calcitonin generelated peptide receptor in the hindlimb vascular bed of the cat and an adrenomedullin receptor. | |||
T70820 | MK-8825 | ||
MK-8825 is a CGRP receptor antagonist. | |||
TP1134 | HCGRP-(8-37) | Human α-CGRP (8-37) | |
Rat CGRP-(8-37) (VTHRLAGLLSRSGGVVKDNFVPTNVGSEAF) is a highly selective CGRP receptor antagonist | |||
T16093 | Telcagepant | MK-0974 | Others |
Telcagepant is an orally active antagonist of calcitonin gene-related peptide (CGRP) receptor (Kis: 0.77 nM and 1.2 nM for human and rhesus CGRP receptors, respectively). | |||
T38734 | Vazegepant | Zavegepant,BHV-3500 | |
Vazegepant is an intranasal CGRP receptor antagonist utilized for conducting acute migraine research. | |||
T30537 | BMS-694153 | BMS694153,BMS 694153 | |
BMS-694153 is a potent and selective CGRP receptor antagonist. | |||
TP2044 | α-CGRP(human) | α-CGRP (human) | |
Endogenous calcitonin gene-related peptide receptor (CGRP) agonist. | |||
T75978 | β-CGRP, human TFA | ||
Human β-CGRP TFA (β-CGRP, human TFA) is a calcitonin peptide that functions through interaction with the calcitonin-receptor-like receptor (CRLR) and receptor-activity-modifying protein (RAMP) complex, demonstrating IC50... |